The biochemical changes that occur during the “silent period” and their physiological consequences are still being established. While some patients may appear mostly healthy, others may experience hypoglycemia, fatigue, abdominal pain, or growth impediments. A focus of the Foundation is to study what happens in the body during the “silent period” and if there are compensatory pathways or genetic factors that may help patients cope during this period, as well as possible triggers of Adolescent and Adult Citrin Deficiency (AACD)* and how to prevent them.
* Previously known as Citrullinemia type 2 (CTLN2)
